Potassium chloride (KCl) is a high-risk medication. The WHO/Joint Commission recommends that health-care organisations have systems and processes in place for the promotion of safe practices with potassium chloride and other concentrated electrolyte solutions. For hospitals that do not currently have a potassium policy in place, this document can form the basis of such a policy. The guideline below replaces the previous version published by the IMSN in 2013